ADRENALINE-INDUCED MORPHOFUNCTIONAL AND IMMUNOHISTOCHEMICAL CHANGES IN THE PANCREAS OF EXPERIMENTAL RATS
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Keywords

pancreas, adrenaline stress, Ki-67, BCL-6, morphometry, immunohistochemistry, endocrine adaptation.

Abstract

Background

Chronic activation of the sympathoadrenal system plays an important role in the development of pancreatic dysfunction. However, morphological mechanisms underlying endocrine and exocrine pancreatic adaptation to prolonged adrenaline exposure remain insufficiently investigated.

Objective.To evaluate morphological, morphometric, and immunohistochemical changes in the pancreas of rats subjected to prolonged adrenaline-induced stress.

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