Vol. 3 No. 4 (2025), Articles
Vol. 3 No. 4 (2025)

PARODONTIT RIVOJLANISHIDA OG‘IZ PATOLOGIK MIKROFLORASINING ROLI

Articles
Published 2025-10-20
Nishanov Ergashali Jo‘raxon o‘g‘li
Urganch davlat tibbiyot instituti Tibbiy profilaktika ishi, sog‘liqni saqlashni boshqarish va xorijiy talabalar fakulteti talabasi
Kenjayeva Maftunaxon Xushnudbek qizi
RANCH texnologiya universiteti Tibbiyot fakulteti Stomatologiya yo‘nalishi talabasi
Kalandarova Umida Arslonovna
Urganch davlat tibbiyot instituti “Fiziologiya va patologik fiziologiya” kafedrasi katta o‘qituvchisi, PhD
PDF

Keywords

Tish biomahsuloti, simbioz, disbioz, yallig‘lanish, periodontal kasallik.

Abstract

Periodontal kasalliklarning boshlanishi va rivojlanishining asosiy etiologik omili bu tish blyashkasi (dental plaque) biomahsuloti  bo‘lib, u murakkab hujayralararo matritsa ichida yashovchi mikroorganizmlarning tartibli to‘plamidan iborat.Nospetsifik blyashka gipotezasi periodontal kasalliklar patogenezida dental biomahsulotining rolini tushuntirishga qaratilgan ilk urinish bo‘lgan.Biroq, zamonaviy diagnostik va laboratoriya tahlillarining joriy etilishi periodontal kasallik (periodontit) rivojlanishi faqatgina tish blyashkasi biomassasining ko‘payishi bilan cheklanmasligini ko‘rsatdi. Darhaqiqat, ko‘p turdagi bakteriyalardan tashkil topgan biomahsulotlar bakteriyalar va odam organizmi o‘rtasida murakkab o‘zaro ta’sirlarni namoyon etadi.

PDF

References

1. Hajishengallis G. Periodontitis: from microbial immune subversion to systemic inflammation. Nat Rev Immunol. 2015;15(1):30–19.

2. 2. Baeza M, Morales A, Cisterna C, et al. Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis. J Appl Oral Sci. 2020;28:e20190248.

3. Chapple IL, Genco R. Diabetes and periodontal diseases: consensus report of the joint EFP/AAP workshop on periodontitis and systemic diseases. J Periodontol. 2013;84(4 Suppl):S106–112.

4. Hirschfeld J, Chapple IL. Periodontitis and systemic diseases: clinical evidence and biological plausibility. Berlin: Quintessenz Verlag; 2021.

5. Bui FQ, Almeida-da-Silva CLC, Huynh B, et al. Association between periodontal pathogens and systemic disease. Biomed J. 2019;42(1):27–35. DOI:10.1016/j.bj.2018.12.001

6. Ohki T, Itabashi Y, Kohno T, et al. Detection of periodontal bacteria in thrombi of patients with acute myocardial infarction by polymerase chain reaction. Am Heart J. 2012;163(2):164–167. DOI:10.1016/j.ahj.2011.10.012

7. Linden GJ, McClean K, Young I, et al. Persistently raised C-reactive protein levels are associated with advanced periodontal disease. J Clin Periodontol. 2008;35(9):741–747.

8. Paraskevas S, Huizinga JD, Loos BG. A systematic review and meta-analyses on C-reactive protein in relation to periodontitis. J Clin Periodontol. 2008;35(4):277–290.

9. Botelho J, Machado V, Leira Y, et al. Economic burden of periodontitis in the United States and Europe: an updated estimation. J Periodontol. 2022;93(3):373–379.

10. Loesche WJ. Chemotherapy of dental plaque infections. Oral Sci Rev. 1976;9:65–107.