ANTIBIOTIKLARGA REZISTENT BAKTERIYALAR BILAN BOG‘LIQ INFEKSIYALARNI DAVOLASHNING ZAMONAVIY YONDASHUVLAR
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Keywords

antibiotik rezistentligi, bakteriyalar, infeksiya, farmakoterapiya, bakteriofag terapiyasi, antimikrob peptidlar, kombinatsiyalangan davolash, dori vositalari.

Abstract

Ushbu maqolada antibiotiklarga rezistent bakteriyalar bilan bog‘liq infeksiyalarni davolash muammolari va ularni bartaraf etishning zamonaviy yondashuvlari tahlil qilingan. Antibiotiklar insoniyat tarixida eng muhim farmakologik kashfiyotlardan biri bo‘lishiga qaramay, ularning keng va ba’zan asossiz qo‘llanilishi natijasida ko‘plab mikroorganizmlar turli dori vositalariga chidamli shakllarga ega bo‘ldi. Bugungi kunda antibiotiklarga rezistent bakteriyalar sog‘liqni saqlash tizimida global xavf sifatida baholanmoqda. Maqolada antibiotik rezistentligi mexanizmlari, ularni aniqlash usullari, yangi avlod antibakterial vositalar va alternativ davolash strategiyalari (bakteriofag terapiyasi, antimikrob peptidlar, kombinatsiyalangan farmakoterapiya) haqida ma’lumotlar keltirilgan. Shuningdek, antibiotiklarni oqilona qo‘llash, infeksiya nazorati, immun tizimini mustahkamlash hamda farmatsevtik nazoratni kuchaytirish orqali davolash samaradorligini oshirish yo‘llari ko‘rib chiqilgan. Ushbu tadqiqot natijalari tibbiy amaliyotda antibiotiklarga chidamli infeksiyalarni oldini olish va samarali davolash uchun ilmiy asos bo‘lib xizmat qiladi.

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