GIPOTALAMO–GIPOFIZAR–TUXUMDON O‘QI VA HAYZ SIKLINI BOSHQARISH MEXANIZMI
PDF

Keywords

Gipotalamo–gipofizar–tuxumdon o‘qi, hayz sikli, gormonal regulyatsiya, gonadotropinlar, reproduktiv salomatlik, estrogen, progesteron, neyroendokrin mexanizm

Abstract

Gipotalamo–gipofizar–tuxumdon (GGTO) o‘qi ayollarda hayz siklini boshqaruvchi asosiy neyroendokrin mexanizm bo‘lib, reproduktiv salomatlik va gormonal muvozanat uchun muhim hisoblanadi. Ushbu maqola GGTO o‘qi tarkibi, gormonlararo o‘zaro ta’sir va hayz sikli davomida siklik o‘zgarishlarni tahlil qiladi. Shuningdek, patologik holatlar va disfunksiyalarni aniqlash va davolashda GGTO o‘qining klinik ahamiyati ko‘rib chiqiladi.

PDF

References

1. Naftolin, F., Khafaga, A., & Nachtigall, M. (2019). The Hypothalamic-Hypophyseal-Ovarian Axis and the Menstrual Cycle. ISGE Series. Springer. glowm.com+1

2. Harris, G. W., & Naftolin, F. (1970). The hypothalamus and control of ovulation. Br Med Bull, 26(1), 3–9. link.springer.com

3. Hall, J. E. (2019). Neuroendocrine control of the menstrual cycle. In Yen and Jaffe’s Reproductive Endocrinology (8th ed., pp. 149–166). Elsevier. link.springer.com+2ucsfhealth.org+2

4. Naftolin, F., Garcia-Segura, L. M., Horvath, T. L., Zsarnovszky, A., Demir, N., Fadiel, A., Leranth, C., Vondracek-Klepper, S., Lewis, C., Chang, A., Parducz, A. (2007). Estrogen-induced hypothalamic synaptic plasticity and pituitary sensitization in the control of the estrogen-induced gonadotrophin surge. Reprod Sci, 14(2), 101–116. link.springer.com

5. Yvinec, R., Crépieux, P., Reiter, E., Poupon, A., & Clément, F. (2018). Advances in computational modeling approaches in pituitary gonadotropin signaling. arXiv. arxiv.org

6. Graham, E. J., Elhadad, N., & Albers, D. (2020). Reduced model for female endocrine dynamics: Validation and functional variations. arXiv. arxiv.org

7. Kawamori, A., Fukaya, K., Kitazawa, M., & Ishiguro, M. (2017). A self-excited threshold autoregressive state-space model for menstrual cycles: forecasting menstruation and identifying ovarian phases based on basal body temperature. arXiv. arxiv.org

8. Blakemore, J., & Naftolin, F. (2016). Aromatase: contributions to physiology and disease in women and men. Physiology (Bethesda), 31(4), 258–269. link.springer.com

9. Palumbo, A., Ávila, J., & Naftolin, F. (2016). The ovarian renin-angiotensin system (OVRAS): a major factor in ovarian function and disease. Reprod Sci, 23(12), 1644–1655. link.springer.com

10. Naftolin, F., & Tolis, G. (1978). Neuroendocrine regulation of the menstrual cycle. Clin Obstet Gynecol, 21(7), 17–29. link.springer.com