Keywords
Abstract
Allergik rinit (AR) — burun shilliq qavatining turli xil allergenlarga organizmning immun javobi sababli yuzaga keladigan yallig‘lanishidir. Ushbu kasallik dunyoda eng keng tarqalgan surunkali holatlardan biri bo‘lib, bemorlarning kundalik hayotiga jiddiy ta'sir ko‘rsatadi, uyquning buzilishi, diqqatning susayishi va umumiy ish qobiliyatining pasayishiga sabab bo‘ladi. Dunyo bo‘yicha AR bilan kasallanishning ortishi eng samarali va xavfsiz davolash usullarini izlash zarurligini ta'kidlaydi. Ushbu maqolada asosiy dori vositalari guruhlari, jumladan intranazal glyukokortikosteroidlar (INGKS), ikkinchi avlod antigistaminlari va ularning kombinatsiyalarining samaradorligi, xavfsizligi va o‘zlashtirilishi batafsil tahlil qilinadi. Shuningdek, xalqaro ARIA (Allergic Rhinitis and its Impact on Asthma) tashabbusining dolzarb tavsiyalari ko‘rib chiqilib, shifokorlarga har bir bemorning individual xususiyatlarini hisobga olgan holda eng mos terapiya usullarini tanlashda yordam beradi [1], [2]. Ma'lumotlarga ko‘ra, INGKS o‘rtacha va og‘ir AR holatlarida afzal hisoblanadi, antigistamin preparatlar esa engil holatlarda va ko‘z simptomlari ustun bo‘lgan bemorlarda samaralidir. Monoterapiya yetarli bo‘lmagan hollarda kombinatsion terapiya tavsiya etiladi.
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