REFERRED PAIN: MECHANISMS, DIAGNOSIS, AND CLINICAL SIGNIFICANCE
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Keywords

Referred pain, nociception, somatic pain, visceral pain, central nervous system, pain perception, clinical diagnosis.

Abstract

Referred pain is a phenomenon in which pain is perceived at a location other than its actual source. This occurs due to the convergence of nerve pathways in the central nervous system. This article explores the mechanisms underlying referred pain, common examples, diagnostic approaches, and its clinical significance. Understanding referred pain is essential for accurate diagnosis and effective treatment planning.
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References

1. Bogduk, N. (2009). "On the definitions and physiology of back pain, referred pain, and radicular pain." Pain, 147(1-3), 17-19.

2. Cervero, F., & Lumb, B. M. (1996). "Visceral pain: The neurophysiological mechanisms." Progress in Neurobiology, 48(4-5), 325-344.

3. Giamberardino, M. A. (2003). "Referred muscle pain and hyperalgesia." Journal of Musculoskeletal Pain, 11(2), 15-22.

4. Keay, K. A., & Bandler, R. (2002). "The neural substrates of visceral and referred pain." Behavioral and Brain Sciences, 25(4), 495-513.

5. Merskey, H., & Bogduk, N. (1994). "Classification of Chronic Pain: Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms." IASP Press.

6. Nijs, J., Van Houdenhove, B., & Oostendorp, R. A. (2010). "Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practice." Manual Therapy, 15(2), 135-141.

7. Scholz, J., & Woolf, C. J. (2002). "Can we conquer pain?" Nature Neuroscience, 5(11), 1062-1067.

8. Tracey, I., & Mantyh, P. W. (2007). "The cerebral signature for pain perception and its modulation." Neuron, 55(3), 377-391.

9. Wall, P. D., & Melzack, R. (2006). "Textbook of Pain." Elsevier Health Sciences.

10. Woolf, C. J. (2011). "Central sensitization: Implications for the diagnosis and treatment of pain." Pain, 152(3 Suppl), S2-S15.