Keywords
Abstract
The results of an experimental model of alloxan-induced osteopathy in white rats are presented. A comprehensive assessment of body weight dynamics, glycemic levels, clinical status, and behavioral responses was conducted over 28 days after alloxan administration. The development of persistent hyperglycemia, polyuria, weight loss, and signs of general exhaustion, accompanied by decreased motor activity and anxiety, was observed. The data obtained confirm the reproducibility of the alloxan-induced diabetes model and its suitability for subsequent morphological and biochemical studies of bone disorders.
References
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