Vol. 1 No. 9 (2025), Articles
Vol. 1 No. 9 (2025)

NERV TIZIMI GISTOGENEZI

Articles
Published 2025-05-27
Qurbonov Akobir Uyg’un o’g’li
Toshkent Tibbiyot Akademiyasi 4-kurs talabasi
Rahmonqulov Alferid To’lqin o’g’li
Toshkent Tibbiyot Akademiyasi 3-kurs talabasi
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Keywords

Neyrogenez, neyrodegerativ kasalliklar, nerv plastinkasi, xorda, neyroblastlar, gen ekspressiyasi, glioblastlar.

Abstract

Nerv tizimi gistogenezi — embrional rivojlanish davrida nerv tizimining shakllanishi va differentsiatsiyasini oʻz ichiga olgan murakkab biologik jarayon. Ushbu maqolada nerv tizimi gistogenezining asosiy bosqichlari: neyrogenez, neyron migratsiyasi, differentsiatsiya va sinapsogenez koʻrib chiqilgan. Tadqiqotlar shuni koʻrsatadiki, bu jarayonlar Wnt, Notch va SHH kabi signal yoʻllari va Pax6, Sox2 kabi transkripsion omillar tomonidan tartibga solinadi. Nerv tizimi gistogenezining buzilishi neyrodegenerativ kasalliklar, miya shikastlanishi va rivojlanish nuqsonlariga olib kelishi mumkin. Maqolada shuningdek, regenerativ tibbiyot va neyronal ildiz hujayralarining klinik ahamiyati haqida soʻz yuritilgan. Tadqiqot natijalari nerv tizimi kasalliklarini tushunish va davolash uchun yangi yoʻnalishlarni yaratish imkoniyatini beradi.

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