GEMOLITIK KASALLIKLAR VA YANGI TUG'ILGAN CHAQALOQLARDA Rh-KONFLIKT MEXANIZMI
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Keywords

Rh-konflikt, yangi tug'ilgan chaqaloqning gemolitik kasalligi, eritrotsitlar gemolizi, bilirubin ensefalopatiyasi, anti-Rh antitelalar, fototerapiya, almashtiruvchi qon quyish.

Abstract

Yangi tug'ilgan chaqaloqlarning gemolitik kasalligi (YTGK) ona va homila o'rtasidagi immunologik ziddiyat natijasida rivojlanib, neonatal davrning og'ir patologiyalaridan biri hisoblanadi. Mazkur maqolada Rh-konflikt mexanizmining immunologik asoslari, gemolitik jarayonning patofiziologik bosqichlari, klinik shakllari hamda diagnostika mezonlari adabiyotlar tahlili asosida yoritilgan. Shuningdek, O'zbekiston Respublikasi Sog'liqni saqlash vazirligi va Respublika ixtisoslashtirilgan gematologiya markazining ma'lumotlari asosida respublikada YTGKning uchrash darajasi, profilaktik chora-tadbirlar samaradorligi tahlil qilingan. Rh-konfliktda ona organizmida ishlab chiqarilgan anti-Rh antitelalar homila eritrotsitlarini gemolizga uchratib, anemiyaning og'ir shakllari, bilirubin ensefalopatiyasi va boshqa asoratlarga olib keladi.

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