Vol. 1 No. 9 (2025), Articles
Vol. 1 No. 9 (2025)

ENDOCRINE CHANGES DURING MENOPAUSE AND THEIR GYNECOLOGICAL SIGNIFICANCE

Articles
Published 2025-09-23
Barnoxonim Yuldasheva
Alfraganus University, Faculty of Medicine 4th-year Medical Student, Clinical Internship
Rahmatullayeva Aziza Farxodovna
Scientific Advisor Gynecologist, Pediatric Gynecologist
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Keywords

Menopause, endocrine changes, estrogen deficiency, progesterone, gynecological health, urogenital atrophy, osteoporosis, cardiovascular risk, hormone replacement therapy

Abstract

Menopause represents a significant transitional period in a woman’s life characterized by the cessation of ovarian function and profound endocrine changes. The decline in estrogen and progesterone production leads to systemic physiological alterations, affecting reproductive health, bone density, cardiovascular function, and metabolic balance. These hormonal shifts have direct gynecological implications, including changes in menstrual patterns, increased risk of urogenital atrophy, and susceptibility to gynecological disorders such as endometrial hyperplasia and pelvic organ prolapse. This article reviews the endocrine adaptations during menopause and explores their clinical and gynecological significance, emphasizing the importance of monitoring and managing menopausal symptoms to optimize women’s health and quality of life.

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