Vol. 1 No. 8 (2025), Articles
Vol. 1 No. 8 (2025)

HORMONAL CONTRACEPTION: MECHANISM AND LONG-TERM EFFECTS

Articles
Published 2025-09-23
Barnoxonim Yuldasheva
Alfraganus University, Faculty of Medicine 4th-year Medical Student, Clinical Internship
Rahmatullayeva Aziza Farxodovna
Scientific Advisor Gynecologist, Pediatric Gynecologist
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Keywords

Hormonal contraception, combined oral contraceptives, progestin-only methods, mechanism of action, long-term effects, reproductive health, menstrual regulation, gynecological disorders

Abstract

Hormonal contraception is one of the most widely used methods for preventing unintended pregnancies worldwide. These contraceptives primarily include combined estrogen-progestin formulations and progestin-only preparations, which regulate the female reproductive system by inhibiting ovulation, altering cervical mucus, and modifying endometrial receptivity. Beyond contraception, hormonal methods can influence menstrual patterns, reduce dysmenorrhea, and manage certain gynecological disorders. However, long-term use may be associated with metabolic, cardiovascular, and reproductive health effects. This article reviews the mechanisms of action of hormonal contraceptives and discusses their potential long-term impacts on women’s health, emphasizing the importance of individualized clinical guidance.

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