Keywords
Abstract
Ushbu maqolada kollagen–xitozan biopolimer matritsasida gidroksiapatit (GAp) nanozarrachalarini sintez qilish usullari va ularning to‘qima muhandisligi hamda regenerativ tibbiyotdagi ahamiyati ko‘rib chiqilgan. Gidroksiapatitni olishning kimyoviy cho‘ktirish, zol-gel, gidrotermal va biomimetik usullari tahlil qilinib, ularning material xossalariga ta’siri yoritilgan. Kollagen–xitozan matritsasida in situ minerallanish jarayonining afzalliklari, organik va noorganik fazalar o‘rtasidagi o‘zaro ta’sirlar hamda hosil bo‘lgan kompozitlarning biofaolligi, osteokonduktivligi va biodegradatsiya xususiyatlari bayon etilgan.
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