Vol. 1 No. 7 (2026), Articles
Vol. 1 No. 7 (2026)

THE IMPORTANCE OF STATINS IN BRONCHIAL ASTHMA

Articles
Published 2026-04-27
Akhmedova Gulchehra Abdullayevna
Acting Associate Professor, PhD, Department of Internal Medicine No.1, Samarkand State Medical University.
Kholjigitova Mukhayyo Berdikulovna
DSc, Associate Professor, Department of Internal Diseases No. 4, Faculty of Medicine, Samarkand State Medical University.
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Keywords

bronchial asthma, statins, inflammation, IL-6, TNF-α, bronchial hyperresponsiveness, immunomodulation.

Abstract

Bronchial asthma is a chronic inflammatory disease of the airways characterized by bronchial hyperresponsiveness and reversible airflow obstruction. In recent years, it has been recognized that not only allergic but also systemic inflammatory mechanisms play an important role in its pathogenesis. Statins (HMG-CoA reductase inhibitors), primarily used as lipid-lowering agents, also possess anti-inflammatory, immunomodulatory, and endothelial-protective properties. This thesis analyzes the potential clinical significance and therapeutic role of statins in bronchial asthma.

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