Vol. 2 No. 5 (2026), Articles
Vol. 2 No. 5 (2026)

INSON ICHAK MIKROFLORASI VA BAKTERIYALARNING UNING GOMEOSTAZIGA TA’SIRI

Articles
Published 2026-02-10
Belyalova Liana Ernesovna
Samarqand davlat tibbiyot universiteti, Davolash ishi fakultetining 3-bosqich talabasi
Umidova Shaxzoda Umidovna
Samarqand davlat tibbiyot universiteti, Davolash ishi fakultetining 2-bosqich talabasi
Nizamitdinova Shaxzoda Djamshedovna
Samarqand davlat tibbiyot universiteti, Pediatriya fakultetining 3-bosqich talabasi
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Keywords

ichak mikroflorasi, bakteriyalar, gomeostaz, disbiyoz, metabolik regulyatsiya, immun tizimi, yallig‘lanish mediatorlari, gastrointestinal ekotizim, probiotiklar, shilliq qavat himoyasi.

Abstract

Inson ichak mikroflorasi — gastrointestinal tizimda joylashgan murakkab mikrobial ekotizim bo‘lib, u tuzilishi va funktsiyasi orqali inson organizmning gomeostazini saqlashda muhim rol o‘ynaydi. Ichak mikroflorasi enterositlar metabolizmi, immun tizimi faolligi, yallig‘lanish mediatorlari regulyatsiyasi va to‘qima himoyasi kabi jarayonlarda ishtirok etadi. Mikrobial disbalans yoki disbiyoz holatlari metabolik sindrom, immun yetishmovchiligi, o‘tkir va surunkali yallig‘lanish kasalliklari, shuningdek, ichak hamda ekstragastrointestinal patologiyalarda klinik oqibatlarga olib kelishi mumkin. Mazkur maqolada inson ichak mikroflorasi tuzilishi, uning gomeostazni tartibga soluvchi mexanizmlari, bakterial kolonizatsiya bilan bog‘liq fiziologik va patofiziologik jarayonlar keng qamrovda tahlil qilinadi.                                          

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