Keywords
Abstract
Rutin (rutozid, vitamin P guruhi flavonoidlari vakili) o‘simliklarda keng tarqalgan bioflavonoid bo‘lib, uning fizikaviy, biologik va farmatsevtik xossalari mavjud. U sariq rangli kristall modda bo‘lib, suvda yomon, lekin etanol va organik erituvchilarda yaxshi eriydi. Masalan, qaynab turgan metanolning 7 ml da 1 g, rutin yana piridin, formamid va ishqorda eriydi ammo petrole efirida amalda erimaydi. Rutin kapillyar devorlarini mustahkamlash, antioksidantlik, yallig‘lanishga qarshi va C vitamini bilan sinergik taʼsir ko‘rsatishi bilan ahamiyatlidir. Buning sababi uning antioksidant, yallig’lanishga qarshi, allergiyaga qarshi, antivirus va antikanserogen xossalari turli o’smalarga qarshi, antidiareya, antimutatsiya, miokardni himoyalash, immunitetni modulyatsiyalash va superoksid radikallarini bog’lash ta’sirlarini keltirib chiqaradi. Farmatsevtikada esa u yurak-qon tomir kasalliklari, gemorragik diatez va gipertenziya davolashda ishlatiladigan preparatlar tarkibiga kiradi. Demak, rutin biologik faol flavonoid sifatida tibbiyot va farmatsevtika amaliyotida katta ahamiyatga ega.
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