Keywords
Abstract
Ushbu maqolada zamonaviy nevrologiya va psixiatriyada keng muhokama qilinayotgan ikki muhim muammo — “tungi oyoq sindromi” (Restless Legs Syndrome — RLS) va psixomotor bezovtalik holatlari tahlil qilinadi. Ularning paydo bo‘lishida neyrotransmitter tizimlari, xususan dopamin va temir almashinuvining buzilishi, markaziy asab tizimi faoliyatidagi disbalans asosiy o‘rin tutishi ko‘rsatiladi. Klinik belgilari, etiopatogenezi va patofiziologik mexanizmlariga oid nazariy yondashuvlar tahlil qilinib, diagnostika va davolashdagi zamonaviy usullar keltiriladi.
References
1. Allen R. P., Picchietti D. L., Garcia-Borreguero D., et al. Restless legs syndrome/Willis–Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group consensus. Sleep Medicine. 2014.
2. Trenkwalder C., Paulus W., Walters A. S. The restless legs syndrome. The Lancet Neurology. 2015;14(10):1037–1046.
3. Winkelmann J., Schormair B. Genetics of restless legs syndrome. Sleep Medicine Reviews. 2017;33:109–117.
4. Silber M. H., Becker P. M., Earley C. J., et al. Willis-Ekbom Disease Foundation revised consensus statement on the management of restless legs syndrome. Mayo Clinic Proceedings. 2013;88(9):977–986.
5. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). 2013.
6. Taylor S. E. Health Psychology. 10th edition. McGraw-Hill Education, 2020.
7. Chervin R. D. Sleep disorders in adults and children: A practical guide. Cambridge University Press, 2017.
8. Rasch B., Born J. About sleep’s role in memory. Physiological Reviews. 2013;93(2):681–766.